Glutathione and bupropion. Jan 30, 2023 · Learn about bupropion usage and dosing. It is a secondary amino compound, a member of monochlorobenzenes and an aromatic ketone. It works by reducing cravings for nicotine. It increases norepinephrine and dopamine in the brain, hormones that help regulate mood. Jul 24, 2025 · Detailed Bupropion dosage information for adults. See full list on drugs. Of the total drug interactions, 218 are major, 339 are moderate, and 5 are minor. Wellbutrin XL Interactions There are 562 drugs known to interact with Wellbutrin XL (bupropion), along with 7 disease interactions, and 1 alcohol/food interaction. Some patients continue to experience symptoms of depression despite trying multiple medications (known as treatment-resistant depression). What is bupropion and what does it treat? Bupropion is an antidepressant medication that works in the brain. Used for: depression, major depressive disorder, seasonal affective disorder Bupropion (Zyban) is a prescription medication that may also be used as a treatment for ADHD, nicotine withdrawal effects, SAD, bipolar, and depression. When your doctor prescribes it, they will give you detailed instructions on how to use it. Includes Auvelity side effects, dose, interactions, and more. Dosage Consumer information about the medication BUPROPION - ORAL (Wellbutrin), includes side effects, drug interactions, recommended dosages, and storage information. [16][17] It is also popular as an add-on medication in the cases of "incomplete response" to the first-line selective serotonin Nov 18, 2024 · Find patient medical information for Bupropion (Wellbutrin, Zyban, and others) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Sep 1, 2025 · Bupropion is sold under different brand names. . However, a small number of people (especially people younger than 25) who take antidepressants for any condition may experience new or worsening INDICATION APLENZIN ® (bupropion hydrobromide extended-release tablets) is a prescription medicine used to treat adults with a certain type of depression called major depressive disorder, and for the prevention of autumn-winter seasonal depression (seasonal affective disorder). com Furthermore, at a dose of 5 mg/kg (i. This medicine is available only with your doctor's prescription. Jun 11, 2018 · Wellbutrin, also called bupropion, is a norepinephrine-dopamine reuptake inhibitor (NDRI) used to treat major depressive disorder, seasonal affective disorder, and may even help people quit smoking. Jan 27, 2025 · Learn more about the dosage of Bupropion XL and Bupropion SR, including available strengths, form, how it’s taken, and more. Includes dosages for Depression, Smoking Cessation and Seasonal Affective Disorder; plus renal, liver and dialysis adjustments. Bupropion (Aplenzin, Wellbutrin, Wellbutrin SR, Wellbutrin XL) is used to treat depression. It is based on bupropion hydrochloride and glutathione (the active ingredients of Wellbutrin and L-glutathione, respectively), and Wellbutrin and L-glutathione (the brand names). Administration: Immediate-release tablets should be taken at least 6 hours apart to minimize the risk of seizures. It is generally safe at recommended doses, but there can be serious side effects, the most notable being seizures. Bupropion and naltrexone will not treat any weight-related medical condition, such as high blood pressure, diabetes, or high cholesterol. What is bupropion? Bupropion is a medication that has been used to treat depression and seasonal affective disorder. Bupropion hydrochloride (HCL) is an antidepressant used for smoking cessation and to treat a variety of conditions, including depression and other mental/mood disorders. If you are already taking medicine for depression or to help you stop smoking, discuss this with your doctor before taking bupropion. Learn about side effects, warnings, dosage, and more. Oct 17, 2022 · Wellbutrin is a brand-name prescription drug used to treat certain types of depression. Includes: indications, dosage, adverse reactions and pharmacology. Therefore, it is important to determine the place in May 26, 2021 · Bupropion hydrochloride ER oral tablets are generic drugs used to treat certain types of depression. Nov 8, 2024 · An overview of Wellbutrin Wellbutrin is a brand name for the drug bupropion—a type of antidepressant known as an “atypical” antidepressant. Bupropion typically is taken orally in the form of bupropion hydrochloride. p. It has a role as an antidepressant, an environmental contaminant and a xenobiotic. The article includes descriptions, uses, drug interactions, and side effects. Access a concise, easily scannable summary on the drug Bupropion. 3 Bupropion has been used to Feb 17, 2020 · Includes BuPROPion indications, dosage/administration, pharmacology, mechanism/onset/duration of action, half-life, dosage forms, interactions, warnings, adverse Jul 1, 2023 · This sheet is about exposure to bupropion in pregnancy and while breastfeeding. Read more about the prescription drug BUPROPION - ORAL. Common brands containing bupropion include Wellbutrin®, Zyban®, and Contrave®. Explore how it works and clinical trial updates. However, a small number of people (especially people younger than 25) who take antidepressants for any condition may experience This systematic review and meta-analysis identified 51 studies, dividing into four categories: bupropion as a sole antidepressant, bupropion coprescribed with another antidepressant, bupropion in ‘other’ populations (e. Bupropion is an aromatic ketone that is propiophenone carrying a tert-butylamino group at position 2 and a chloro substituent at position 3 on the phenyl ring. Sep 12, 2025 · Some supplements can interfere with medications in potentially dangerous ways. Apr 4, 2025 · Wellbutrin, which is used to treat certain types of depression, can cause side effects. 1 Its unique mechanism of action among antidepressants is thought to be due to reuptake of dopamine and norepinephrine. S. Sep 2, 2024 · Bupropion is an antidepressant medication that has received FDA approval for the treatment of depression and seasonal affective disorder and as an aid for smoking cessation. Bupropion is a medication that is most commonly prescribed to treat depression, quit smoking, and lose weight. Bupropion is an aminoketone-derivative antidepressant and smoking deterrent. This video is part of a collaboration with the National Cancer Institute’s Smokefree. It is approved for the treatment of major depressive disorder (MDD), seasonal affective disorder (SAD), and to help people quit smoking (smoking cessation). Dec 13, 2024 · Bupropion is an antidepressant medication. It is very important that you receive only one prescription at a time for bupropion. Jun 30, 2025 · Wellbutrin is prescribed to treat major depressive disorder and prevent seasonal affective disorder. Aug 29, 2025 · Bupropion, drug that is used to treat depression, to prevent depression in persons with seasonal affective disorder, or sometimes to aid in smoking cessation. Feb 21, 2025 · Extended release bupropion hydrobromide, an oral monotherapy, is more effective in relieving symptoms of treatment resistant depression than past drugs. Jun 28, 2024 · Bupropion hydrochloride extended-release tablets USP (SR), 100 mg of bupropion hydrochloride, USP are blue, round, biconvex, film-coated tablets debossed with “S” on one side and “522” on the Bupropion is a drug used in the treatment of depression. Bupropion (Aplenzin, Wellbutrin XL) is also used to treat seasonal affective disorder (SAD; episodes of depression that occur at the same time each year [usually in the fall and winter but rarely may occur in the spring or summer months]). It is based on bupropion hydrochloride and glutathione (the active ingredients of Wellbutrin and L-glutathione, respectively), and Wellbutrin and L-glutathione (the brand names). Since its approval in 1985, bupropion has been utilized off-label for various conditions, including antidepressant-induced sexual dysfunction, depression associated with bipolar disorder, obesity, and ADHD in pediatric Sep 24, 2023 · Learn about the side effects of bupropion, from common to rare, for consumers and healthcare professionals. Sexual side effects and weight gain are less likely with Wellbutrin compared to other antidepressants. Barbon et al. Report any new or worsening symptoms to your doctor, such as Sep 2, 2024 · Bupropion is an antidepressant medication that has received FDA approval for the treatment of depression and seasonal affective disorder and as an aid for smoking cessation. These can include Bupropion This information from Lexicomp explains what you need to know about this medication, including what it’s used for, how to take it, its side effects, and when to call your healthcare provider. Learn about dosage, side effects, uses, and more. Learn more here. Bupropion is 1 of many treatment options available for depression and is associated with several side effects as well as the potential for misuse. Bupropion is a norepinephrine and dopamine reuptake inhibitor used in the treatment of major depressive disorder (MDD), seasonal affective disorder (SAD), and as an aid to smoking cessation. Report any new or worsening symptoms to your doctor, such as: mood or behavior Aug 20, 2024 · Read on for bupropion dosage information, including typical dosage, adjustments for health conditions, and what to do if you miss a dose. Antidepressants can help prevent suicidal thoughts/attempts and provide other important benefits. Apr 23, 2024 · Bupropion is an antidepressant used for depression, seasonal affective disorder, smoking cessation, and weight loss by targeting dopamine and norepinephrine. Describes the medication bupropion (Wellbutrin, Wellbutrin SR, Wellbutrin XL, Zyban, Aplenzin, Forfivo XL) an antidepressant drug used to manage depression, and also to help with smoking cessation. Experts also explain why certain supplements shouldn’t be taken together. Jul 28, 2025 · Easy-to-read patient tips for wellbutrin covering how it works, benefits, risks, and best practices. Jul 24, 2025 · Wellbutrin SR side effects Get emergency medical help if you have signs of an allergic reaction (hives, itching, fever, swollen glands, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling). Learn about its more common, mild, and serious side effects and how to manage them. Since its approval in 1985, bupropion has been utilized off-label for various conditions, including antidepressant-induced sex … Jul 24, 2025 · Wellbutrin XL: side effects, dosage, interactions, FAQs, reviews. Dosage: Typically started at 100 mg twice a day, which may be increased to 100 mg three times a day. Bupropion was developed in 1966 and patented in 1974 by What is Wellbutrin, and how does it work? Used to treat depression, Wellbutrin is also known as the generic name bupropion. The risk of side effects may be increased with higher daily doses of bupropion; therefore, it is important to determine the appropriate dosing for bupropion for the treatment of depression. What is this medication? BUPROPION (byoo PROE pee on) treats depression. Learn about side effects, dosages, drug interactions, warnings, and more. Bupropion hydrochloride tablets are contraindicated in patients with a current or prior diagnosis of Nov 18, 2024 · Find patient medical information for Bupropion (Wellbutrin, Zyban, and others) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Jul 13, 2025 · Bupropion package insert / prescribing information for healthcare professionals. Learn how bupropion interacts with alcohol, whether it is safe, and the potential side effects. Bupropion has also been reported to improve enzymatic antioxidant defense (15). Dec 12, 2022 · This information from Lexicomp® explains what you need to know about this medication, including what it’s used for, how to take it, its side effects, and when to call your healthcare provider. Feb 29, 2024 · Bupropion hydrochloride tablets are contraindicated in patients with a seizure disorder. g. It belongs to a group of medications called NDRIs. Nov 14, 2024 · Wellbutrin (bupropion) is a prescription drug used to treat depression in adults. Jun 3, 2025 · Wellbutrin (bupropion) is an antidepressant medication that treats health conditions like depression and seasonal affective disorder. Serious neuropsychiatric events, including but not limited to depression, suicidal ideation, suicide attempt, and completed suicide have been reported in patients taking bupropion for smoking Jul 26, 2024 · Bupropion is available in three different formulations: Regular, Sustained-Release (SR), and Extended-Release (XL). Jan 9, 2025 · Bupropion is used to treat depression and seasonal affective disorder. There are 562 drugs known to interact with bupropion, along with 7 disease interactions, and 1 alcohol/food interaction. IMPORTANT SAFETY INFORMATION Mar 24, 2025 · Bupropion and naltrexone is a combination medicine used to help manage weight in obese or overweight adults with weight-related medical problems. ), bupropion prevented increases in MDA and nitrate levels and a decrease in reduced glutathione (GSH) levels in morphine-treated rats, suggesting its antioxidant activity (14). Evidence-based interaction details between Bupropion, Naltrexone (brand name (s): Contrave) and Glutathione, including interaction severity and how likely the interaction is to occur. Aug 15, 2023 · Wellbutrin (bupropion) is used to treat major depressive disorder and seasonal affective disorder. Common Wellbutrin side effects include tremors, agitation, and dry mouth. Food and Drug Administration (FDA) in 1989 for the treatment of depression. Furthermore, at a dose of 5 mg/kg (i. Although uncommon, serious Wellbutrin side effects are possible. Learn about the dextromethorphan-bupropion combination for depression, its uses, dosage, side effects, and interactions. bupropion and naltrexone is used together with diet and exercise. Always consult your doctor before taking a new supplement. bipolar depression, elderly populations) and primary evaluation of side effects. It is important to take the medication exactly as directed to minimize adverse effects. Each formulation has specific dosing schedules and uses. Bupropion, formerly called amfebutamone, [15] and sold under the brand name Wellbutrin among others, is an atypical antidepressant that is indicated in the treatment of major depressive disorder and seasonal affective disorder and to support smoking cessation. Most antidepressants work by increasing levels of serotonin in your brain, but Wellbutrin works by increasing levels of dopamine and norepinephrine—two neurotransmitters or brain chemicals that are responsible for keeping you energized, alert, and Sir: Bupropion is an antidepressant originally approved by the U. However, because bupropion is a selective norepinephrine and dopamine reuptake inhibitor with no serotonergic activity, common antidepressant-associated side effects, such as sexual dysfunction, weight gain, and sedation, are not associated with bupropion therapy. Bupropion is a drug used in the treatment of depression. It should not take the place of medical care and advice from your healthcare provider. Bupropion (Wellbutrin) treats depression. Brand names […] Bupropion is an antidepressant used for smoking cessation and to treat a variety of conditions, including depression and other mental/mood disorders. Jul 24, 2025 · BuPROPion (Eqv-Wellbutrin SR) side effects Get emergency medical help if you have signs of an allergic reaction (hives, itching, fever, swollen glands, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling). Learn about the drug’s dosages and more. Includes Wellbutrin side effects, interactions and indications. Aug 13, 2024 · Learn common interactions to know about when taking bupropion (Wellbutrin), including medication and alcohol interactions. Zyban is a brand of bupropion, which is a medication that helps you quit smoking. Oct 3, 2024 · Bupropion and dextromethorphan (Auvelity) is an antidepressant medicine used to treat major Depressive Disorder (MDD). Jul 10, 2025 · buPROPion reference guide for safe and effective use from the American Society of Health-System Pharmacists (AHFS DI). This video offers general instructions on how to use bupropion SR to quit smoking. Use in Smoking Cessation Treatment: WELLBUTRIN®, WELLBUTRIN SR®, and WELLBUTRIN XL® are not approved for smoking cessation treatment, but bupropion under the name ZYBAN® is approved for this use. It helps regulate your mood by increasing norepinephrine and dopamine hormones in your brain. Elsevier’s Monographs offer are a quick and easy way to find evidence-based answers to your clinical questions. Bupropion SR is a prescription medicine approved by the FDA to help people quit smoking. Bupropion has demonstrated efficacy comparable to that of other antidepressants. Learn about side effects, dosage, alternatives, interactions, and more. Medscape - Depression, smoking cessation-specific dosing for Wellbutrin XL, Aplenzin (bupropion), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information. Jul 10, 2015 · Our data show that NAC interacts selectively with different ADs, indicating that specificities in how different agents affect glutamate function are of relevance. Read the latest news and reviews about the drug as well as potential side effects and popular alternatives. gov Initiative. 2 In 1997, the FDA approved bupropion sustained release (SR) for the treatment of smoking cessation. Bupropion is an antidepressant medication that works in the brain. (2006) concluded that desipramine exerts moderate but selective effects on glutamate receptor expression and editing. This information is based on available published literature. Learn about mild to serious side effects it can cause and how to manage them. Sep 9, 2025 · Easy-to-read patient tips for bupropion covering how it works, benefits, risks, and best practices. ufzdfi khoxlf ltarar lrrbhu isofh hsrxmo qvmtzp ascqts xqnce olktg